What is SGPT?
What is SGPT?how does this affect the humanbody?does it harm if the level is 104?
You have not mentioned the unit and the technique how ever the value of
104 is high. Thalidomide as such does not cause its increase but the
associated disease might cause it to increase.
Alanine aminotransferase(ALT) or SGPT
Alanine aminotransferase (ALT), formerly called serum glutamate pyruvate
transaminase, or SGPT, is an enzyme necessary for energy production. It
is present in a number of tissues, including the liver, heart, and
skeletal muscles, but is found in the highest concentration in the
liver. Because of this, it is used in conjunction with other liver
enzymes to detect liver disease, especially hepatitis or cirrhosis
without jaundice. Additionally, in conjunction with the aspartate
aminotransferase test (AST), it helps to distinguish between heart
damage and liver tissue damage.
Aspartate aminotransferase
Aspartate aminotransferase (AST), formerly called serum
glutamic-oxaloacetic transaminase, or SGOT, is another enzyme necessary
for energy production. It, too, may be elevated in liver and heart
disease. In liver disease, the AST increase is usually less than the ALT
increase. However, in liver disease caused by alcohol use, the AST
increase may be two or three times greater than the ALT increase.
Normal results
Reference ranges vary from laboratory to laboratory and also depend upon
the method used. However, normal values can generally be found within
the following ranges, unless specified differently.
ALT: 5-35 IU/L (values for the elderly may be slightly higher, and values also may be higher in men and in African-Americans)
AST: 0-35 IU/L
Abnormal results
ALT: Values are significantly increased in cases of hepatitis, and
moderately increased in cirrhosis, liver tumor, obstructive jaundice,
and severe burns. Values are mildly increased in pancreatitis, heart
attack, infectious mononucleosis, and shock. Most useful when compared
with ALP levels.
AST: High levels may indicate liver cell damage, hepatitis, heart attack, heart failure, or gall stones.
Categories:
SGPT,
What is SGPT?
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